Actively Recruiting
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Led by Tianjin Medical University Cancer Institute and Hospital · Updated on 2023-09-28
1362
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules. Non-solid nodules rarely develop mediastinal lymph node metastasis. The present study is a prospective, multicenter and randomized clinical trial, comparing the overall survival and disease-free survival of whether performing mediastinal lymph node dissection in non-small cell lung cancer with ground-glass nodule CT features.
CONDITIONS
Official Title
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Thin-slice HRCT shows single ground-glass nodule with consolidation-to-tumor ratio of 0.5 or less and no lymph node metastasis
- Clinical stage IA non-small cell lung cancer diagnosed before or during surgery
- No history of other malignancies within past 5 years or previous lung surgery
- No anti-cancer treatment before surgery
You will not qualify if you...
- Presence of simultaneous or metachronous double cancers within past 5 years
- Active bacterial or fungal infection
- Interstitial pneumonitis, pulmonary fibrosis, or severe pulmonary emphysema
- Use of systemic steroid medication
- Uncontrolled diabetes mellitus
- Uncontrolled hypertension or severe heart disease or heart failure history
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ethics review board of Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, China, 300060
Actively Recruiting
Research Team
Z
Zhenfa Zhang, MD
CONTACT
C
Chenguang Li, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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