Actively Recruiting
Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
Led by HealthPartners Institute · Updated on 2025-07-29
64
Participants Needed
1
Research Sites
115 weeks
Total Duration
On this page
Sponsors
H
HealthPartners Institute
Lead Sponsor
U
University of Minnesota
Collaborating Sponsor
AI-Summary
What this Trial Is About
Many patients with advanced pancreatic cancer and colorectal cancer experience burdensome and difficult-to-treat symptoms. The impact of multiple symptoms (called "symptom burden") can negatively affect a patient's quality of life, decrease their ability to tolerate cancer treatments, and lead to worse survival. Current approaches to manage these cancer-associated symptoms often work poorly, with most patients reporting a moderate to severe symptom burden. Therefore, there is an urgent need for treatments that improve these symptoms in patients with advanced pancreatic and colorectal cancer, and data suggests that medical cannabis can help. In this research study, we are examining the usefulness of using medical cannabis in patients with advanced pancreatic cancer and colorectal cancer to further study how cannabis can impact their symptom burden.
CONDITIONS
Official Title
Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 or older
- Diagnosed with pancreatic or colorectal cancer confirmed by tissue biopsy
- Cancer is advanced (locally advanced or metastatic) with no planned curative surgery in next 3 months
- Experienced nausea, vomiting, appetite loss, wasting, or pain at least once in past 14 days
- Starting or recently started standard chemotherapy (excluding immunotherapy) within past 2 weeks
- Resident of Minnesota
- Willing to register and follow rules of Minnesota Medical Cannabis Program
- Willing to report baseline and ongoing patient-reported outcomes
You will not qualify if you...
- Regular use of THC cannabis products 10 or more days in past 30 days
- History of intolerance or hypersensitivity to cannabis
- Diagnosis of Alzheimer's dementia, active epilepsy, or past traumatic brain injury
- Known active or untreated brain metastases
- Receiving immunotherapy or investigational cancer treatments
- Women who are pregnant, breastfeeding, or of childbearing potential without birth control
- Uncontrolled medical or psychiatric conditions that increase risks or interfere with study
- Any condition that may endanger safety or affect study compliance per investigator judgment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
HealthPartners Cancer Research Center
Saint Louis Park, Minnesota, United States, 55426
Actively Recruiting
Research Team
A
Alissa Gavenda, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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