Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06150326

Medical Honey for Wound Treatment in Intensive Care. (MICARéa) Randomized, Controlled, Single-center Pilot Study.

Led by University Hospital, Angers · Updated on 2026-04-06

60

Participants Needed

1

Research Sites

198 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Wound management is a real public health issue in France. To date, a wide range of devices exists to treat these wounds, depending on their nature and stage of evolution. Honey has been proposed for the care of wounds and is effective in reducing the surface of wounds and the pain perceived by patients. Inanition, its use is very simple compared to usual care, requiring different types of dressing accross time. In the intensive care unit, patients are prone to suffering or developing numerous types of wound, but the interest of honey has not been investigated yet. We propose a prospective, monocentric, randomized, single-blind, controlled clinical trial to assess the efficacy of managing acute cutaneous wounds with honey (Activon®) compared with standard care, in intensive care patients. The primary endpoint is the percentage of wound surface area reduction measured at 15 days from inclusion.

CONDITIONS

Official Title

Medical Honey for Wound Treatment in Intensive Care. (MICARéa) Randomized, Controlled, Single-center Pilot Study.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalized in surgical intensive care unit A -USC PTO CHU ANGERS
  • Signed informed consent by patient or relative (or emergency inclusion procedure)
  • One or more wounds at least 4 cm2 in size, evolving for less than 8 days, including stage 2, 3, 4 pressure sores, lacerations, ulcers, dermabrasions, and scar disunions
Not Eligible

You will not qualify if you...

  • Honey intolerance or allergy to bee stings
  • Wounds lasting more than 8 days
  • Bleeding wounds
  • Tunneled wounds
  • Chronic dermatoses
  • Estimated life expectancy less than 15 days
  • Expected discharge within 48 hours
  • No affiliation to a French social security scheme
  • Pregnant, breastfeeding, or parturient women
  • Person deprived of liberty by judicial or administrative decision
  • Person under legal protection measure

AI-Screening

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Trial Site Locations

Total: 1 location

1

Angers University Hospital, surgical reanimation

Angers, France

Actively Recruiting

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Research Team

C

Catherine CR ROD, NURSE

CONTACT

S

Sigismond SL LASOCKI, PUPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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