Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
NCT06550297

Medically Tailored Meals for Cardiovascular Health

Led by Columbia University · Updated on 2025-10-24

160

Participants Needed

1

Research Sites

91 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

A

American Heart Association

Collaborating Sponsor

AI-Summary

What this Trial Is About

This randomized clinical trial (RCT) will investigate novel approaches to enhance effectiveness, engagement, reach, and cost-effectiveness of medically tailored meals (MTM) programs for promoting cardiovascular health, focusing on economically disadvantaged New York City neighborhoods with a disparate burden of multiple cardiometabolic diseases. The main questions the RCT aims to answer are: 1. Does enhancing MTM programs, with culturally relevant cardiovascular health curriculum (including educational sessions on heart health, healthy diet, cooking demonstrations, recipes, gift bags with healthy ingredients and fresh produce, and addressing social needs) enhance program engagement and effectiveness in improving short-term healthy eating behaviors and clinical outcomes (HbA1c and blood pressure) among individuals with type 2 diabetes and elevated to high blood pressure who currently qualify for MTM programs? 2. Is the MTM program coupled with the cardiovascular health curriculum effective for improving healthy eating behaviors and clinical outcomes (HbA1c and blood pressure) among individuals with type 2 diabetes and elevated to high blood pressure who do not currently qualify for MTM programs and is a gradual reduction of MTM dosing an effective and sustainable approach for expanding reach of these programs? To answer question 1, 60 participants with type 2 diabetes and elevated to high blood pressure who currently qualify for MTM programs will be randomized into a group that receives the standard MTM program (10 MTMs/week for 8 months) or a group that receives the standard program plus the cardiovascular health curriculum. To answer question 2, 100 participants with type 2 diabetes and elevated to high blood pressure who do not currently qualify for MTM programs (due to not having advanced disease with complications) will be randomized into a group that receives the standard MTM program (10 MTMs/week for 8 months) plus the cardiovascular health curriculum or a group that receives standard MTM program for the first 3 months followed by a gradual reduction in dosing of the MTMs by 50% over the remaining 5 months plus the CVH curriculum. All participants will have their HbA1c and blood pressure measured and complete questionnaires about their diet quality, health and lifestyle behaviors, and program engagement and implementation at baseline, 3 months, and 8 months.

CONDITIONS

Official Title

Medically Tailored Meals for Cardiovascular Health

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 20 years or older
  • For Cohort A: Type 2 diabetes diagnosis with hypertension or elevated blood pressure
  • For Cohort B: Type 2 diabetes diagnosis or HbA1c ≥ 6.5% or diabetes medication use
  • For Cohort B: Hypertension diagnosis or elevated blood pressure or hypertension medication use
  • English or Spanish speaking
  • Able to provide informed consent and complete study requirements
Not Eligible

You will not qualify if you...

  • Cancer diagnosis or undergoing cancer treatment
  • Non-English and non-Spanish speaking
  • Unable to complete study requirements due to cognitive or psychiatric conditions
  • Severe psychiatric disorders
  • Health issues preventing safe participation or affecting study outcomes (e.g., substance use disorder, dialysis, neurodegenerative conditions)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Columbia University Mailman School of Public Health

New York, New York, United States, 10032

Actively Recruiting

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Research Team

R

Research Project Coordinator

CONTACT

N

Nour Makarem, PhD, FAHA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

4

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Medically Tailored Meals for Cardiovascular Health | DecenTrialz