Actively Recruiting
Supporting Tailored Adaptive Change and Reinforcement for Medication Adherence Program: Randomized Trial of a Novel Approach to Improve Adherence in Older Hypertensive Women and Men
Led by Tulane University · Updated on 2026-05-20
402
Participants Needed
5
Research Sites
N/A
Total Duration
On this page
Sponsors
T
Tulane University
Lead Sponsor
O
Ohio State University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach designed to improve medication adherence, blood pressure control, and quality of life for adults aged 40 and older with hypertension. This randomized controlled trial compares the STAR-MAP program with medication reminder tools alone among participants who have uncontrolled blood pressure and low adherence to antihypertensive medication. Participants are randomly assigned to one of two groups: one receives interactive health coaching sessions alongside medication reminder tools, while the other receives only the medication reminder tools. The coaching involves 11 sessions over one year, focusing on adaptive strategies to encourage better medication-taking behaviors. The study collects data at baseline, 6 months, 12 months, and 24 months. Throughout the study, participants undergo questionnaires, physical measurements including height, weight, and blood pressure, a computerized test of implicit associations, and laboratory analysis of urine for medication metabolites. Researchers aim to measure medication adherence using various scales and lab tests, blood pressure control, and health-related quality of life. The main outcome is the difference in medication adherence proportion at 12 months. Safety and progress are monitored over the two-year follow-up period.
CONDITIONS
Brief Title
Medication Adherence Program
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fully insured by Blue Cross Blue Shield of Louisiana (BCBSLA)
- Continuously enrolled in BCBSLA for one year
- Planning to remain a member of BCBSLA for the next year
- English-speaking
- Telephone access
- Aged 40 years or older
- Diagnosis of essential hypertension (ICD-10-CM code I10)
- Currently filling antihypertensive medication prescriptions
- Low antihypertensive medication refill (proportion of days covered less than 0.8)
- Low self-reported adherence (Krousel-Wood Medication Adherence Scale score 1 or higher)
- Uncontrolled blood pressure (systolic BP 130 mm Hg or higher or diastolic BP 80 mm Hg or higher)
- Desire to improve blood pressure
You will not qualify if you...
- Living in a household with someone already enrolled in the study
- Enrollment in another clinical trial for drug adherence or blood pressure control
- Moderate to severe cognitive impairment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or via telephone)
Duration - 11 sessions over one year
Participants receive either interactive health coaching combined with medication reminder tools or medication reminder tools only to improve medication adherence.
11 coaching sessions over one year
Trial Site Locations
Total: 5 locations
1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
Actively Recruiting
2
Tulane Doctors Dermatology & Multispecialty Clinic
Covington, Louisiana, United States, 70433
Actively Recruiting
3
Tulane Doctors Heart & Vascular and Primary Care Clinic
Metairie, Louisiana, United States, 70002
Actively Recruiting
4
Tulane University Clinical and Translational Unit
New Orleans, Louisiana, United States, 70112
Actively Recruiting
5
LSU Health Sciences Shreveport Clinical Trials Office
Shreveport, Louisiana, United States, 71101
Actively Recruiting
Research Team
E
Erin M Peacock, PhD, MPH
M
Marie A Krousel-Wood, MD, MSPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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