Actively Recruiting
MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence
Led by Roswell Park Cancer Institute · Updated on 2026-03-24
150
Participants Needed
1
Research Sites
215 weeks
Total Duration
On this page
Sponsors
R
Roswell Park Cancer Institute
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial identifies and addresses barriers to pediatric medication adherence among families of children with acute lymphoblastic leukemia. Pediatric nonadherence (noncompliance) to medication is a significant public health problem, and rigorous research repeatedly documents that nonadherence increases risk for hospitalization, healthcare cost, disease progression, and death. Pediatric acute lymphoblastic leukemia (ALL) patients who miss 5% of 6-mercaptopurine (6-MP) doses within the 2-year 6-MP regimen have a 2.7-fold risk of cancer that comes back after a period of improvement (relapse). To address these families' needs, researchers have developed MedSupport, a theory-based multilevel intervention with targets at the organizational, healthcare team, and caregiver levels that is designed to address root barriers to medication adherence. This study is being done to better understand families' experiences giving their child oral chemotherapy at home and to help families cope with the day-to-day challenges of giving their child medication.
CONDITIONS
Official Title
MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Parent of a child diagnosed and receiving first line therapy for acute lymphoblastic leukemia (ALL) at a study site
- Child is between 365 days (1 year) and under 19 years old at study entry
- Child's therapy includes 6-mercaptopurine (6-MP) administered orally or by nasogastric tube
- Parent has verbal fluency in English, French, or Spanish
- Parent has a smartphone or computer with Internet access
- Parent understands the study and signs informed consent before any study procedures
You will not qualify if you...
- Parent is unwilling or unable to follow study protocol requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here