Actively Recruiting

Phase 4
Age: 18Years - 60Years
All Genders
NCT06380491

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Led by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Updated on 2026-04-01

50

Participants Needed

1

Research Sites

239 weeks

Total Duration

On this page

Sponsors

I

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Lead Sponsor

U

Universidad Nacional Autonoma de Mexico

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if melatonin works to treat comorbid insomnia in adults with OSA and nocturnal non-dipping blood pressure pattern. The main question it aims to answer is: Does melatonin maintain sleep during night and recover the dipping blood pressure pattern?

CONDITIONS

Official Title

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Polisomnographic diagnosis of Obstructive Sleep Apnea
  • Non-dipping blood pressure on Ambulatory blood pressure monitoring (ABPM)
Not Eligible

You will not qualify if you...

  • Use of sleep or psychiatric medication
  • Use of Positive Airway Pressure (CPAP or Bipap)
  • Neurologic or psychiatric disorder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ)

Mexico City, Mexico

Actively Recruiting

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Research Team

M

Matilde Valencia-Flores, PhD

CONTACT

M

Maria V Santiago, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA) | DecenTrialz