Assessment of postoperative pain after Mohs micrographic surgery.
Boonyapat Limthongkul, Faramarz Samie, Tatyana R Humphreys
https://pubmed.ncbi.nlm.nih.gov/23464845Actively Recruiting
Led by University of Oklahoma · Updated on 2025-12-15
300
Participants Needed
1
Research Sites
8 weeks
Total Duration
This research aims to explore alternative methods for managing postoperative pain in patients undergoing Mohs micrographic surgery, a precise technique for removing certain skin cancers. The study focuses on comparing different pain control options to improve comfort and overall well-being after surgery. Researchers hope to provide better information to the Mohs surgery community and offer patients a potential new choice of pain medication with fewer side effects than standard options. Participants will be randomly assigned to one of three groups: one group will receive a single dose of Meloxicam 7.5 mg followed by acetaminophen 500 mg as needed, another group will receive a single dose of Meloxicam 15 mg followed by acetaminophen 500 mg as needed, and the control group will take a single dose of acetaminophen 500 mg followed by alternating ibuprofen 200 mg and acetaminophen 500 mg every three hours, which is the current standard of care. Meloxicam will be given orally right after the surgical wound closure. During the study, participants will complete surveys about their pain levels and satisfaction with pain control. Researchers will monitor pain from enrollment until suture removal or wound check, typically between 7 to 21 days post-surgery. The study will evaluate how well Meloxicam controls pain compared to the standard pain medications. Safety and patient experience will be carefully observed throughout the trial period, which runs until August 2026.
CONDITIONS
Meloxicam in Mohs Micrographic Surgery
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 7 to 21 days
Participants receive a mandatory single dose of Meloxicam or standard pain medication immediately after Mohs surgery closure, followed by as-needed acetaminophen or alternating acetaminophen and ibuprofen for pain control.
1 treatment visit (in-person) upon completion of surgery and medication use as needed at home
Duration - 7 to 21 days
Participants are monitored through suture removal, wound check, or flap takedown to assess postoperative pain and recovery.
1 to 2 follow-up visits depending on surgical closure type
Total: 1 location
1
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Actively Recruiting
C
Chase Pitchford, MD
L
Landon Hendrickson, MD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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