Actively Recruiting

Phase Not Applicable
Age: 8Years +
All Genders
NCT06969066

Memory Training in Insomnia With Cognitive Impairment

Led by Xuanwu Hospital, Beijing · Updated on 2025-05-28

70

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial investigates the effects of Cognitive Remediation Therapy (CRT) on chronic insomnia (CI) with mild cognitive impairment.

CONDITIONS

Official Title

Memory Training in Insomnia With Cognitive Impairment

Who Can Participate

Age: 8Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Insomnia Disorder according to DSM-5
  • Pittsburgh Sleep Quality Index (PSQI) total score greater than 5
  • Age 8 years or older
  • Voluntary participation with signed informed consent
  • Right-handedness
  • Age between 55 and 75 years
  • Education duration of 12 years or more
  • At least junior high school education level
  • Meets Petersen's criteria for mild cognitive impairment with subjective memory complaints lasting 3 months or more
  • Global Deterioration Scale (GDS) stage 1-2 and Clinical Dementia Rating (CDR) score 0-0.5
  • Memory test scores at least 1.5 standard deviations below age- and education-matched norms: MMSE 24 or higher, MoCA less than 26, ADL score above 26
  • Memory impairment as the main deficit with preserved function in other cognitive areas
  • Normal daily functioning
  • No dementia or major physical or psychiatric disorders affecting brain function
Not Eligible

You will not qualify if you...

  • Severe physical illnesses or major psychiatric disorders, or risk of suicide
  • Diagnosed or suspected sleep breathing disorders, restless legs syndrome, circadian rhythm sleep disorders, or shift work
  • Pregnancy or breastfeeding
  • Currently receiving any psychological therapy
  • History of infectious diseases such as syphilis or HIV

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xuanwu Hospital, Capital Medical University

Beijing, China, 100053

Actively Recruiting

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Research Team

H

Hongxing Wang, MD & PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Memory Training in Insomnia With Cognitive Impairment | DecenTrialz