Study of Blood Clotting Changes in Adults Undergoing Tumor Surgery for Meningioma or Glioma Compared to Healthy Controls

What this Trial Is About

Researchers are investigating the risk of blood clot complications in patients undergoing meningioma tumor surgery. This observational trial studies how tumor removal affects blood clotting and platelet function, aiming to understand the molecular changes involved. Blood samples from meningioma patients are compared with those from patients having glioma surgery and healthy controls to identify differences in coagulation related to these tumors. Participants include patients having surgery to remove meningioma or glioma tumors, as well as healthy individuals without tumors or surgery. Blood samples are collected before and immediately after tumor removal to assess changes in blood clotting activity. The control groups help provide comparison data to better understand the effects specific to meningioma surgery. During the study, participants provide blood samples for laboratory analysis focused on tissue factor changes during the few hours of surgical tumor removal. Researchers monitor coagulation and platelet function to measure how surgery impacts blood clot risk. The study is led by University Hospital Tuebingen and will continue through August 2026. Participants may be healthy volunteers or patients meeting the criteria, with no upper age limit specified.

Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation