Actively Recruiting
Menopause Effects on Cortico-reticular Functioning
Led by University of Jyvaskyla · Updated on 2026-05-01
20
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Post-menopausal women who request to begin hormone-replacement therapy (HRT) are directed to the research team. The participants are tested before beginning HRT, after two months of HRT, and five months of HRT. Tests include strength performance, central nervous system functioning, body composition, resting metabolic rate, and vascular screening. The participants are provided a 12-week training intervention (2 x strength, 2 x endurance per week) that can be voluntarily followed between tests at month 2 and 5. Compliance with the training program is recorded. A minimum of 15 participants are needed a priori, but the investigators aim to recruit and test 20 women.
CONDITIONS
Official Title
Menopause Effects on Cortico-reticular Functioning
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 6 months since last menstrual period but no more than 5 years post-menopausal
- Basal follicular-stimulating hormone concentration greater than 30 IU/L (confirmed after recruitment)
- Willing to start combined hormonal treatment
- Womb and ovaries intact with normal function throughout reproductive age
- Willing to provide informed consent
- No exclusion criteria for transcranial magnetic stimulation measurements according to Rossi et al. (2021)
You will not qualify if you...
- Body mass index greater than 35 kg/m2 (excessive obesity)
- Using an intra-uterine device during transition to menopause
- Cardiovascular or musculoskeletal disease preventing strenuous physical activity
- Current smoker
- Diagnosed psychiatric illness
- Epilepsy
- Other diagnosed injuries or illnesses affecting the neuromuscular system
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Jyväskylä
Jyväskylä, Finland, 40014
Actively Recruiting
Research Team
S
Simon Walker Dr (Dos.), PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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