Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05985447

Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity

Led by Heinrich-Heine University, Duesseldorf · Updated on 2023-08-14

180

Participants Needed

1

Research Sites

247 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Women and men show marked differences in cardiovascular risk profile and outcome. Women experience fewer cardiovascular events than men before menopause, but this relationship seems to reverse at menopause. These disparities are probably due to hormonal factors, especially the female sex hormone estrogen seems to have a protective influence on the development of atherosclerotic plaques premenopausal. The underlying mechanisms of the effect of estrogens on the vessel wall are still insufficiently investigated. In this study, menopause related effects on leukocyte distribution and function as well on platelets and their aggregational response will be evaluated.

CONDITIONS

Official Title

Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years
  • Male, female, diverse patients with current treatment in the Department of Cardiology, Pneumology and Angiology
  • Persons who are able to understand and follow the instructions of the study staff
  • Written informed consent
Not Eligible

You will not qualify if you...

  • Age < 18 years
  • Lack of written consent to participate in the study
  • Coagulation disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University-Hospital Düsseldorf Division of Cardiology, Pulmonary Disease and Vascular Medicine

Düsseldorf, Germany, 40225

Actively Recruiting

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Research Team

L

Lisa Dannenberg, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity | DecenTrialz