Actively Recruiting
Mentalization Based Treatment (MBT) in Help Seeking Youths With a Clinical High-Risk Condition for Psychosis (CHR-P)
Led by Marco Armando · Updated on 2025-11-25
212
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this study is to evaluate the efficacy of Mentalization-Based Treatment (MBT) combined with Need-Based Clinical Interventions (NBCI) compared to NBCI alone, on CHR-P diagnostic statuses and symptom expression (Hypothesis 1). Specifically, the investigator will assess diagnostic outcomes using a 3-level variable: transition to psychosis, CHR-P status quo, and remission out of CHR-P, as well as CHR-P symptom expression. The investigator hypothesize that: (1a) the experimental treatment (MBT + NBCI) will have a significant effect on diagnostic status (i.e. transition to psychosis) at the end of treatment and follow-up; (1b) the experimental treatment (MBT + NBCI) will significantly reduce the severity of psychotic symptoms at the end of treatment and follow-up.
CONDITIONS
Official Title
Mentalization Based Treatment (MBT) in Help Seeking Youths With a Clinical High-Risk Condition for Psychosis (CHR-P)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 14-30 years with a CHR-P condition as defined by the SIPS criteria
- Patients who provide informed consent
You will not qualify if you...
- Patients with a prior diagnosis of a psychotic disorder
- Intellectual disability with IQ below 70
- Psychotic symptoms primarily caused by substance misuse
- Significant language barriers
- Parents or legal guardians not providing consent for minors
- Adult patients under guardianship
AI-Screening
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Trial Site Locations
Total: 1 location
1
CHUV
Lausanne, Switzerland, 1011
Actively Recruiting
Research Team
M
Marco Armando, Pr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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