Actively Recruiting
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
Led by Mehmet Incebıyik · Updated on 2025-12-18
147
Participants Needed
1
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective clinical study aims to compare the short-term effectiveness, safety, and patient-reported outcomes of two surgical techniques used for the treatment of female stress urinary incontinence (SUI): Pubo-Urethral Ligament Plication (PLP), a mesh-free native tissue repair method, and the Transobturator Tape (TOT) procedure, a commonly used mesh-based mid-urethral sling technique. The study evaluates continence improvement, perioperative and postoperative complications, operative time, hospital stay, postoperative pain, and patient satisfaction. The goal is to provide evidence on whether a mesh-free surgical option such as PLP can offer comparable outcomes to mesh-based TOT, particularly for patients seeking alternatives to synthetic materials.
CONDITIONS
Official Title
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18 to 80 years
- Clinical diagnosis of stress urinary incontinence
- Failure of conservative management such as pelvic floor exercises or medical therapy
- Desire to undergo surgical treatment with PLP or TOT
- Ability to provide informed consent
- Willingness to attend postoperative follow-up visits
You will not qualify if you...
- Mixed urinary incontinence with predominant urge symptoms
- Active urinary tract infection
- Pelvic organ prolapse stage II or higher
- Previous anti-incontinence surgery
- Neurological diseases affecting bladder function
- Pregnancy or planning pregnancy during follow-up
- Uncontrolled diabetes or bleeding disorders
- Contraindications to surgery
- Use of medications affecting bladder function such as anticholinergics
- Inability to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Harran University Research and Application Hospital
Şanliurfa, HALİLİYE, Turkey (Türkiye), 63300
Actively Recruiting
Research Team
M
Mehmet İNCEBIYIK, MD
CONTACT
Ö
Ömer TAMMO, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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