Actively Recruiting

Age: 14Years - 90Years
All Genders
NCT03951311

Metabolic Abnormalities, Lifestyle and Diet Pattern in Heart Failure

Led by Ruijin Hospital · Updated on 2021-10-08

1500

Participants Needed

1

Research Sites

552 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Metabolic abnormalities (e.g., hypertension, diabetes mellitus, dyslipidemia, and obesity) and unhealthy lifestyle behaviors (e.g., smoking and drinking habits, sedentary behavior, sleep disorder and physical inactivity) and unhealthy diet (e.g., high sugar and high fat) are major risk factors for cardiovascular diseases mobility and mortality. The investigators sought to estimate the impact of metabolic abnormalities, lifestyle behavior and diet pattern on prognosis of heart failure. This study planned to consecutively enroll 1,500 participants with heart failure with reduced ejection fraction and heart failure with mid-range ejection fraction fulfilling the inclusion criteria. Each heart failure survivors will be followed up for 5 years. Information on metabolic diseases, lifestyle and diet pattern were obtained through standardized questionnaire. The major adverse cardiac events will be identified by reviewing pertinent medical records and discharge lists from the hospitals, or official death certificates collected at local death registration centers, or directly contacting participants' family. The Cox proportional hazard model will be used to assess the association between metabolic risk factors and lifestyle and diet habits and health outcomes in heart failure patients.

CONDITIONS

Official Title

Metabolic Abnormalities, Lifestyle and Diet Pattern in Heart Failure

Who Can Participate

Age: 14Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 14 years or older
  • Have typical symptoms of heart failure according to the Framingham criteria
  • Have a left ventricular ejection fraction (LVEF) below 50%, including mid-range or reduced ejection fraction, with relevant heart changes or elevated pro-BNP (e.g., 600 pg/mL) confirmed by echocardiography or cardiac MRI
Not Eligible

You will not qualify if you...

  • Younger than 14 years or older than 90 years
  • Currently pregnant
  • Have cancer with a life expectancy less than one year
  • Participating in other clinical trials
  • Have endocarditis, pericardial diseases, or congenital heart diseases
  • Have heart failure caused by non-cardiac diseases such as pulmonary heart disease, infection, infiltration, metabolic problems, severe anemia, sepsis, or arteriovenous fistula
  • Lack informed consent
  • Refuse recommended drug treatment or interventions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

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Research Team

Z

Zhijun Wu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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