Actively Recruiting
Deteriorated Metabolic Control in the Perioperative Period in Surgical Patients: Impact of Anesthetic Preparation and Patient Frailty
Led by Zealand University Hospital · Updated on 2026-05-07
100
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how a standard dose of dexamethasone, given during non-cardiac surgery, affects blood sugar levels in adult patients. It also evaluates whether continuous glucose monitoring (CGM) offers a more accurate way to track blood sugar changes compared to traditional finger-prick tests. The study involves adult patients undergoing elective non-cardiac surgery lasting more than one hour, who receive dexamethasone as part of their anesthesia care. Participants will have a CGM device placed on their upper arm about 12 hours before surgery, which will stay in place for up to 10 days after the operation. During this time, blood sugar levels will be measured continuously by the CGM and intermittently by finger-prick tests. The CGM readings are blinded so that neither patients nor clinicians can see them. No changes will be made to the patients' regular care or treatments due to study participation. Throughout the study, participants will undergo standard surgical and anesthesia procedures while researchers monitor blood sugar patterns before, during, and up to 10 days after surgery. The study will assess the patterns of high blood sugar and compare glucose trends over time. No extra treatments are provided, and the study lasts for the duration of the CGM use and monitoring period.
CONDITIONS
Brief Title
Metabolic Control in Anesthesia and Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years or older) scheduled for elective non-cardiac surgery
- Expected surgery duration longer than 1 hour
- Planned administration of dexamethasone as part of standard anesthesia care
- Ability to provide written informed consent
You will not qualify if you...
- Unable to provide consent or permission
- Known allergy or adverse reaction to dexamethasone
- Diagnosis of type 1 diabetes
- Active infection, sepsis, or immunosuppression
- Contraindications to continuous glucose monitoring (CGM)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 10 days postoperatively
Participants are observed for metabolic control during the perioperative period using continuous glucose monitoring and standard anesthesia care.
Monitoring during hospital stay
Trial Site Locations
Total: 1 location
1
Zealand University Hospital
Roskilde, Denmark, 4000
Actively Recruiting
Research Team
A
Anne M Brinck, MSc Medicine
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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