Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
FEMALE
Healthy Volunteers
NCT05197309

Metabolic Diet for Relapse Prevention in Anorexia Nervosa

Led by Icahn School of Medicine at Mount Sinai · Updated on 2026-02-27

20

Participants Needed

1

Research Sites

210 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored from low weight. Participants will be adult women with anorexia nervosa who have been recently restored to normal weight and adult women with no history of eating disorders. After enrollment, participants will start meeting weekly with a registered dietitian to implement the Metabolic Diet in their daily lives, and will receive medical monitoring for adherence, side effects, changes in metabolic or psychological parameters, and weight stability.

CONDITIONS

Official Title

Metabolic Diet for Relapse Prevention in Anorexia Nervosa

Who Can Participate

Age: 18Years - 40Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female
  • Age between 18 and 40 years
  • Body mass index (BMI) at or above 18.5 kg/m2
  • Speaks English
  • Medically stable as confirmed by a licensed physician with vital signs and blood tests
  • History of anorexia nervosa diagnosis (for weight-restored anorexia nervosa group only)
  • Restored to normal weight from underweight BMI within the past 6 months (for weight-restored anorexia nervosa group only)
Not Eligible

You will not qualify if you...

  • Current or lifetime diagnosis of psychotic or bipolar disorders
  • Active substance use disorders
  • Taking medications that could affect metabolism (must be free from these for 2 weeks before glucose testing)
  • History of suicide attempt in the past 6 months or acute suicide risk
  • Significant current medical illness or metabolic conditions, including diabetes and pregnancy
  • Current or lifetime diagnosis of eating disorders (healthy control group only)
  • Active depressive disorders (healthy control group only)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029

Actively Recruiting

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Research Team

C

Chinara Tate

CONTACT

T

Tom Hildebrandt

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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