Study of Muscle Power Versus Metabolic Power Exercise on Heart and Metabolism in Postmenopausal Women With and Without Breast Cancer

What this Trial Is About

Researchers are evaluating metabolic flexibility and autonomic function, which describe cardiovascular health, in postmenopausal women who have survived breast cancer without recurrence compared to postmenopausal women without cancer. This clinical trial also aims to analyze how two different supervised 8-week exercise programs impact these cardiovascular capacities in these groups. The study focuses on breast cancer, the most common cancer among Spanish women, and its close link to cardiovascular diseases, especially after menopause. Participants will be randomly assigned to one of two exercise interventions lasting 8 weeks a High Intensity Interval Training HIIT program focused on improving metabolic power with 30-minute sessions three times a week, or a Muscle Power Intervention MPI program focused on strength with 45-minute sessions twice a week. Both programs are professionally supervised with adapted intensities. Two cohorts are included postmenopausal breast cancer survivors and postmenopausal women without cancer, each divided between the two exercise programs. During the study, participants will undergo assessments before and after the 8-week interventions, including fat oxidation during an incremental test and analysis of heart rate variability to measure autonomic function. Additional measures include weight, body composition, blood pressure, oxygen saturation, physical activity levels, muscle power, metabolic rate, and heart function. This mixed cross-sectional and longitudinal study is designed to contribute to better cardiovascular health and quality of life for postmenopausal women, with follow-up lasting throughout the 8-week intervention period.

Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study