Actively Recruiting
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Led by Rutgers, The State University of New Jersey · Updated on 2026-05-13
44
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain, and several dietary pattern studies indicate that nuts and legumes are associated with better bone health. In addition, our preliminary translational data indicates that a higher monounsaturated fatty acid (MUFA) intake is associated with improved bone mineral density (BMD) and quality. Given these findings, the proposed study aims to examine the impact of consuming peanut products on bone health, metabolic health (e.g., serum glucose, insulin, lipids and inflammation), markers of brain and sleep health, and physical function in overweight and obese older adults before and after a six-month weight loss intervention using a randomized controlled design. The results of this study have the potential to provide valuable insights into the role of peanuts as a sources of fatty acids in promoting health and preventing disease in at-risk adults.
CONDITIONS
Official Title
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and postmenopausal women (more than 2 years since last menses), ages 50 to 75 years
- Body mass index between 25 and 42 kg/m2 or evidence of pre-clinical obesity
- Agree to be randomly assigned to consume a daily peanut snack or nut-free snack for 24 weeks
- Must attend about 10 on-site visits in New Brunswick, NJ, USA
You will not qualify if you...
- Peanut allergies or intolerances
- Weight loss greater than 5% in the past 6 months or extreme dietary or physical activity habits
- Unable to follow the study intervention or provide required specimens
- Significant psychiatric or food disorders
- Current diagnosis or cancer history in the past 3 years
- Bone diseases, type I or II diabetes, gastrointestinal disease, hyperparathyroidism, untreated thyroid disease, significant immune, liver, heart, or kidney disease
- Uncontrolled high blood pressure or abnormal lipid levels
- Surgery in the past 6 months or weight loss surgery in the past 3 years
- Regular use of medications affecting bone metabolism or gastrointestinal tract
- Recent antibiotic use within the past month
- Alcohol or illicit drug abuse
- Any condition preventing study participation as judged by the research physician
- Participation in another clinical interventional research trial
AI-Screening
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Trial Site Locations
Total: 1 location
1
Rutgers University - NJ Inst Food Nutrition & Health
New Brunswick, New Jersey, United States, 08901
Actively Recruiting
Research Team
P
Principal Investigator
CONTACT
R
Research Manager
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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