Actively Recruiting
Metabolic and Immunomic Differential Analysis of Primary Central Nervous System Diffuse Large B-Cell Lymphoma
Led by Ting YANG · Updated on 2025-11-18
20
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective cohort study. The case group will include patients with primary central nervous system lymphoma confirmed by imaging and pathology. The control group will include patients with pathologically confirmed diffuse large B-cell lymphoma who have been excluded from central nervous system involvement, as well as age- and gender-matched healthy volunteers (hematopoietic stem cell donors). Baseline data (as described below) will be collected. Patients with primary CNS lymphoma will undergo follow-up every 3 months, with immediate follow-up if clinical symptoms arise.
CONDITIONS
Official Title
Metabolic and Immunomic Differential Analysis of Primary Central Nervous System Diffuse Large B-Cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 75 years.
- Confirmed diagnosis of primary central nervous system lymphoma (PCNSL) with no prior antitumor therapy before baseline sample collection.
- Signed informed consent agreeing to participate and provide samples and clinical information.
- Complete supporting imaging and pathology data for PCNSL patients.
You will not qualify if you...
- Presence of other systemic malignancies.
- Severe infections or metabolic disorders.
- Use of antimetabolites or chemotherapy drugs within one week before sample collection.
- Pregnant or lactating women.
- Severe internal medical conditions such as end-stage renal disease, heart failure, or liver failure.
- Psychiatric disorders or cognitive impairment preventing study completion.
AI-Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China
Actively Recruiting
Research Team
晓
晓权 纪
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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