Actively Recruiting
Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
Led by German Diabetes Center · Updated on 2023-08-22
300
Participants Needed
1
Research Sites
574 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the prospective observational DISTEMI-Study in people with and without Diabetes mellitus (DI) after new onset of ST-Segment Elevation Myocardial Infarction (STEMI) aged 18-80 years at inclusion into the study is to characterize in detail the clinical, metabolical, immunological and vascular phenotype, investigate the interplay between myocardial remodelling and the metabolic phenotype, monitor the progression of the disease and compare the phenotype of STEMI people with diabetes mellitus to people with prediabetes and glucose tolerant people.
CONDITIONS
Official Title
Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Condition after new onset of ST-segment elevation myocardial infarction (STEMI)
- Age 18-80 years
- HbA1c <9.0%
- Diagnosis of diabetes mellitus according to ADA and DDG criteria (HbA1c 65.5% and/or pathological oral glucose tolerance test)
- Normal glucose tolerance according to ADA and DDG criteria (HbA1c <5.7% and normal OGTT)
- Impaired glucose metabolism ("prediabetes") according to ADA and DDG criteria (impaired fasting glucose and/or impaired glucose tolerance and/or HbA1c 5.7-6.4%)
- Consent-able, hemodynamically stable people without sedation or interfering medication
You will not qualify if you...
- Diabetes mellitus category 3 A-H (ADA criteria), gestational diabetes
- Current pregnancy
- Infectious diseases, acute infections or fever
- Immunosuppressive therapy
- Severe chronic renal, liver or heart disease (e.g., serum creatinine 61.6 mg/dl, peripheral artery occlusive disease stage IV)
- Malignant diseases
- Severe chronic psychiatric illness or addiction
- Participation in an intervention trial
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
German Diabetes Center
Düsseldorf, North Rhine-Westphalia, Germany, 40225
Actively Recruiting
Research Team
M
Michael Roden, Prof., MD
CONTACT
C
Clara Möser, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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