Actively Recruiting
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
Led by Technical University of Munich · Updated on 2026-03-03
20
Participants Needed
3
Research Sites
225 weeks
Total Duration
On this page
Sponsors
T
Technical University of Munich
Lead Sponsor
H
Helmholtz Zentrum München
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this mono-center pilot trial, surgical patients who are at high risk to be admitted to intensive care will be screened and asked for participation. We are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.
CONDITIONS
Official Title
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Invasive mechanically ventilated critically ill patient with expected intensive care unit stay > 3 days
- Postoperative patient
- 18 years old or older
- American Society of Anesthesiology (ASA) classification III or higher
You will not qualify if you...
- Moribund patient
- Receiving non-curative care (comfort care)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Medical University of Vienna
Vienna, State of Vienna, Austria, 1090
Actively Recruiting
2
Klinikum rechts der Isar, School of Medicine, Technical University of Munich
Munich, Bavaria, Germany, 81675
Active, Not Recruiting
3
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, Germany, 10117
Active, Not Recruiting
Research Team
S
Stefan J Schaller, MD
CONTACT
M
Marian Demitsch
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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