Actively Recruiting

Phase Not Applicable
Age: 16Years - 40Years
All Genders
NCT05827900

Metacognitive Training in Ultra-high Risk

Led by Medical University of Vienna · Updated on 2024-03-15

30

Participants Needed

2

Research Sites

131 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this pilot study is to examine whether metacognitive training can improve symptoms, wellbeing and functioning in individuals with attenuated psychotic symptoms. Metacognitive group training is an intervention designed to raise awareness on and change cognitive biases that may foster the development of psychotic symptoms such as delusions. It has been shown to be helpful in people with manifest psychosis. The main goal is to assess whether this training is prone to reducing symptoms in individuals at risk for psychosis. Participants will be randomized either to treatment as usual or to treatment as usual plus metacognitive training. Follow-ups will be performed over the period of one year.

CONDITIONS

Official Title

Metacognitive Training in Ultra-high Risk

Who Can Participate

Age: 16Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 16 and 40 years
  • Individuals with attenuated psychotic symptoms occurring several times per week within the last year and lasting at least one week but no longer than five years
  • Individuals with brief limited intermittent psychotic symptoms lasting less than one week and spontaneously resolved
  • Ability to give informed consent and follow study procedures
Not Eligible

You will not qualify if you...

  • Past psychotic episode lasting one week or longer, treated or untreated
  • Recent increase in antipsychotic medication dose within the last two weeks or clinical need for dosage increase at inclusion
  • Past neuroleptic exposure exceeding lifetime haloperidol dose of 50 mg equivalent
  • Acute suicidality or aggressive behavior
  • Current symptoms fully explained by acute intoxication
  • Organic brain disease such as epilepsy or inflammatory brain disease
  • Unstable physical illness with psychotropic effects
  • Diagnosis of serious developmental disorder like Asperger's syndrome
  • Premorbid IQ below 70
  • Inadequate knowledge of the German language

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Department of Child and Adolescent Psychiatry

Vienna, Austria

Actively Recruiting

2

Department of Psychiatry and Psychotherapy

Vienna, Austria

Actively Recruiting

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Research Team

N

Nilufar Mossaheb, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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