Actively Recruiting

Early Phase 1
Age: 18Years - 45Years
FEMALE
Healthy Volunteers
NCT05917587

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Led by Anna Stanhewicz, PhD · Updated on 2025-05-13

30

Participants Needed

1

Research Sites

198 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.

CONDITIONS

Official Title

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Who Can Participate

Age: 18Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 12 weeks and no more than 45 years postpartum
  • History of gestational diabetes mellitus (GDM) or healthy pregnancy
Not Eligible

You will not qualify if you...

  • Prediabetes or diabetes with HbA1c 5.7% or higher
  • Current tobacco use
  • Cardiovascular or metabolic disease
  • Taking cardiovascular or metabolic medication
  • History of high blood pressure during pregnancy
  • Currently pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Iowa

Iowa City, Iowa, United States, 52242

Actively Recruiting

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Research Team

A

Anna Stanhewicz, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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