Actively Recruiting
Methacholine Challenge Test (MCT) in Healthy Adults
Led by Allergi- og Lungeklinikken, Elsinore · Updated on 2024-09-19
25
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Knowledge of Methacholine Challenge Test (MCT) and impedance Oscillometry (IOS) is limited. Only three studies have included adult patients, and none of these with healthy controls. The three studies have combined IOS and spirometry in the same test, although it is not recommended to perform IOS after a test that requires deep breathing, e.g. FEV1 measurement. Deep breathing is considered to affect the impedance via reduced tone in the smooth muscle.
CONDITIONS
Official Title
Methacholine Challenge Test (MCT) in Healthy Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Forced expiratory volume in the 1. second (FEV1) >80%
- FEV1/FVC-ratio >0.7
- FeNO <25 pbb
- Oxygen saturation (SatO2) >95%
- Negative methacholine Challenge Test with less than 20% drop in FEV1
You will not qualify if you...
- Any lung disease
- Lung symptoms
- Medicine for lung disease
- Tobacco smoking
- Ex-smokers with more than 5 package years
- BMI (body mass index) >40 kg/m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Thomas Ringbæk
Elsinore, Denmark, 3140
Actively Recruiting
Research Team
T
Thomas Ringbæk, MSci
CONTACT
L
Lars Frolund, MSci
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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