Actively Recruiting
Methamphetamine Cue-reactivity
Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-07-25
88
Participants Needed
1
Research Sites
53 weeks
Total Duration
On this page
Sponsors
I
Icahn School of Medicine at Mount Sinai
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine group-differences between men who have sex with men (MSM) and non-MSM MUD. The primary objective is to identify psychophysiological markers of methamphetamine (MA) cue-reactivity and its abstinence incubation. The secondary objective is to examine group-differences in methamphetamine use disorder (MUD) individuals between homosexual men (MSM) and heterosexual men (non-MSM). The primary endpoint is to assess incubation of cue-reactivity longitudinally with its reduction in cognitive reappraisal, and the secondary endpoint is to examine the impact of cognitive reappraisal on clinical outcomes of methamphetamine use disorder (MUD) in homosexual men (MSM). 2-year long study. Screening and enrollment will be done at different locations of the Addiction Institute of Mount Sinai. The EEG session will be done at Icahn School of Medicine at Mount Sinai. Participation in the research study will be for a single EEG session.
CONDITIONS
Official Title
Methamphetamine Cue-reactivity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and give informed consent
- Identify as either MSM or non-MSM
- Male, age between 18 and 60 years
- DSM-5 diagnosis of methamphetamine use disorder (MUD)
- Current methamphetamine users: 2 weeks abstinent (range 1-3 weeks) or abstinent for 3 months (range 2-4 months)
- Treatment-seeking MUD participants must be in a treatment facility with methamphetamine as the primary drug at first visit
- Treatment-seeking MUD must be abstinent from methamphetamine for about 2 weeks (range 1-3 weeks) at enrollment
You will not qualify if you...
- Women
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029
Actively Recruiting
Research Team
M
Muhammad A Parvaz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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