Actively Recruiting
A Methodological Study to Learn More About Kidney Function in Healthy People and in People With Reduced Kidney Function
Led by Bayer · Updated on 2026-04-17
50
Participants Needed
1
Research Sites
58 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this study is to investigate how reliable a test assessing the renal functional reserve (RFR) and the maximum glomerular filtration rate (maxGFR) are. MaxGFR and RFR assessments are repeated twice at 1-month intervals. If precise, this test may improve the measure of kidney function and be useful in future studies for people with chronic kidney problems. To do this, the researchers will collect and analyze information about kidney function from up to 50 adults, including healthy people and people with stable kidney problems. Each person will come to the study center for a screening visit and then three study days, each about a month apart. On each study day, participants will have blood and urine samples taken before and after drinking a protein shake. The tests will measure things like creatinine, cystatin C, and other markers in the blood and urine to see how the kidneys are working. The study will also record basic health information, weight, blood pressure, and any medicines being taken. The study will last about 2 to 2.5 months for each participant.
CONDITIONS
Official Title
A Methodological Study to Learn More About Kidney Function in Healthy People and in People With Reduced Kidney Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 18 to 75 years inclusive at the time of signing consent
- Stable medical condition with no new drug or treatment prescribed for a chronic condition within 60 days before Study Day 1
- Body weight between 50 and 100 kg
- Female participants must not be pregnant or breastfeeding; must have a confirmed negative urine pregnancy test if applicable
You will not qualify if you...
- Surgical intervention within 60 days before Study Day 1
- New clinical diagnosis within 60 days before Study Day 1
- New drug prescription within 60 days before Study Day 1
- Relevant worsening of any medical condition within 60 days before Study Day 1
- Known congenital amino acid metabolism disorders
- Severe allergy to milk products
- Known liver cirrhosis
- Regular use of non-steroidal anti-inflammatory drugs (NSAIDs)
- Impaired kidney function with estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bayer AG - Occupational Health Services
Berlin, Germany, 13353
Actively Recruiting
Research Team
B
Bayer Clinical Trials Contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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