Actively Recruiting
mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer
Led by Fudan University · Updated on 2025-08-07
30
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the efficacy of mFOLFIRINOX plus radiotherapy to Patients with CA19-9-normal Advanced Pancreatic Cancer.
CONDITIONS
Official Title
mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and willing to sign informed consent
- Age between 18 and 80 years
- ECOG performance status of 0 to 2
- Histologically or cytologically confirmed advanced pancreatic adenocarcinoma
- No prior anti-tumor therapy received
- Baseline serum CA19-9 4 U/mL, CEA 5.2 ng/mL, and CA125 5 U/mL
- At least one measurable lesion based on RECIST criteria
- Expected survival of at least 3 months
- Adequate organ function based on blood tests
- Women of childbearing potential and men agree to use effective contraception throughout the study
You will not qualify if you...
- Pregnant or nursing women
- Previous anti-tumor therapy received
- Baseline serum CA19-9 above 37 U/mL, CEA above 5.2 ng/mL, or CA125 above 35 U/mL
- Diagnosis confirmed as non-adenocarcinoma of the pancreas
- Inflammation of the digestive tract such as pancreatitis, cholecystitis, or cholangitis
- Severe or uncontrolled diseases affecting compliance or result interpretation
- Renal insufficiency or dialysis
- Other serious illnesses that may affect treatment safety
- Allergy to oxaliplatin or other chemotherapy drugs
- Unwillingness or inability to follow study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Cancer Center
Shanghai, China
Actively Recruiting
Research Team
Y
Ying Yang, MD
CONTACT
G
Guopei Luo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here