Actively Recruiting

Phase Not Applicable
Age: 60Years - 85Years
All Genders
NCT05850416

mGlide-Care: A Partnership With Caregivers

Led by University of Minnesota · Updated on 2026-02-13

75

Participants Needed

1

Research Sites

123 weeks

Total Duration

On this page

Sponsors

U

University of Minnesota

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Hypertension (HTN) is the most significant stroke, cardiovascular disease and dementia risk factor and is substantially under-treated especially in older persons. In this study the investigators will develop mGlide-Care to address uncontrolled HTN in people with mild cognitive impairment (MCI) and early stage Alzheimer's Disease and Alzheimer's Disease Related Dementia (AD/ADRD). mGlide-Care is adapted from mGlide which is a mHealth (mobile health technology) mediated care model for HTN care. Aim 1 will engage stakeholders to study the acceptability of mHealth mediated HTN care and will use their input to develop mGlide-Care. Stakeholders are persons with early stage AD/ADRD and MCI, unpaid family caregivers, primary care providers, geriatricians and clinical pharmacists. Aim 2 is a feasibility pilot to test mGlide-Care vs. usual care in 75 participants with uncontrolled HTN and early stage AD/ADRD or MCI. Caregivers will assist participants. Outcomes will include HTN control and participant and caregiver reported measures.

CONDITIONS

Official Title

mGlide-Care: A Partnership With Caregivers

Who Can Participate

Age: 60Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with early stage Alzheimer's disease, Alzheimer's disease related dementia, or mild cognitive impairment
  • Have uncontrolled hypertension
  • Have an unpaid, family caregiver
  • Have an established medical diagnosis of hypertension
  • Speak English
  • Participant or caregiver must have a smartphone or mobile device that can transmit blood pressure data
  • Participant and caregiver must be able and willing to follow the entire study protocol
  • Able to give voluntary written informed consent
Not Eligible

You will not qualify if you...

  • Severe comorbid illness such as end-stage kidney disease or liver disease, or life expectancy less than 1 year
  • Medical complexity that prevents participation in the clinical trial
  • Active use of illicit drugs like cocaine, methamphetamines, opioids, or phencyclidine
  • Participant and caregiver unable to complete study tasks due to homelessness, planned relocation, or leaving the country within 12 months
  • Serious psychiatric illness that impairs treatment or compliance, including schizophrenia or bipolar disorder
  • Unable or unwilling to give consent

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Epidemiology Clinical Research Center

Minneapolis, Minnesota, United States, 55415

Actively Recruiting

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Research Team

K

Kamakshi Lakshminarayan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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