Actively Recruiting
Led by University of California, San Francisco · Updated on 2026-04-01
2100
Participants Needed
3
Research Sites
N/A
Total Duration
U
University of California, San Francisco
Lead Sponsor
P
Post Graduate Institute of Medical Education and Research, Chandigarh
Collaborating Sponsor
This research aims to evaluate a culturally tailored mobile interactive education and support group intervention called MeSSSSage among postpartum Indian women. The study focuses on improving health-related knowledge, behaviors, and outcomes for mothers and newborns, addressing challenges like limited postpartum care access and social isolation. It is a randomized controlled trial involving 2100 women from three diverse Indian states, intending to assess the intervention's impact, mechanisms, and cost-effectiveness. Participants in the intervention group receive 26 education and support sessions over eight months, including two prenatal and weekly postpartum sessions up to six months after birth. The sessions are delivered via audioconference and moderated by community health workers, with additional engagement through a provider-moderated group text chat. The control group receives standard postnatal care. The intervention is designed to supplement usual care and overcome barriers through mobile technology and social support. During the study, participants will be assessed on exclusive breastfeeding, postpartum depression, and family planning adoption at six months. Other outcomes include knowledge of maternal and neonatal danger signs, healthcare use, and infant vaccination. Researchers will monitor participant engagement and analyze how the intervention influences knowledge, social support, self-efficacy, and behaviors. The study also includes cost-effectiveness analyses and will follow participants for eight months to gather comprehensive data on postpartum health and well-being.
CONDITIONS
mHealth India Postnatal Health Intervention Effectiveness
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - From enrollment until birth (approximately 4 to 12 weeks depending on gestational age at enrollment)
Participants join groups of about 20 women and attend two prenatal intervention sessions to prepare for postpartum support.
2 prenatal intervention sessions (phone-based)
Duration - 6 months postpartum
Participants receive weekly group mHealth education and social support sessions via phone for six months postpartum, including interactive voice content, moderated group discussions, and text chats to improve maternal and neonatal health behaviors.
Weekly phone-based group sessions for up to 26 sessions
Duration - Up to 6 months postpartum
Participants are monitored for health-related behaviors and outcomes up to 6 months postpartum to assess intervention effectiveness.
Assessments at 6 months postpartum
Total: 3 locations
1
Post-Graduate Institute for Medical Education and Research
Chandīgarh, Haryana, India
Actively Recruiting
2
Sangath
Bhopal, Madhya Pradesh, India
Actively Recruiting
3
Indraprastha Institute for Information Technology
New Delhi, National Capital Territory of Delhi, India
Not Yet Recruiting
A
Alison M El Ayadi, ScD
N
Nadia G Diamond-Smith, PhD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Alison M El Ayadi, Mona Duggal, Lakshmi Gopalakrishnan...
https://pubmed.ncbi.nlm.nih.gov/40578858