Actively Recruiting
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
Led by University of Michigan · Updated on 2025-09-08
9
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects. Nine subjects will be randomized to 2 split-belt intervention groups (one group where early stance loading is trained and the other where midstance loading is trained) and a placebo group. The goal of this study is to explore the adaptations in knee loading from a 6-week split-belt training intervention. The investigators' main question for this aim is: 1. Does knee loading, measured by the sagittal plane knee moment, change to a greater extent in the split-belt treadmill training groups compared to the placebo group? 2. Are there differences in training-related knee loading changes between individuals trained in the early stance vs. midstance loading split-belt training?
CONDITIONS
Official Title
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 14 to 45 years
- Suffered an acute, complete ACL rupture confirmed by MRI and physical exam
- Underwent ACL reconstruction with autograft within the past 10 months
- Willing to participate in testing and follow-up as outlined in the protocol
- English-speaking
You will not qualify if you...
- Unable to provide written informed consent
- Female subjects who are pregnant or planning to become pregnant (self-reported)
- Previous ACL injury
- Previous surgery to either knee
- Bony fracture accompanying ACL injury
- History of knee dislocation
- ACL reconstruction with an allograft
- Multi-ligamentous and/or staged ACL reconstruction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48176
Actively Recruiting
Research Team
A
Alexa Johnson, PhD
CONTACT
R
Riann M Palmieri-Smith, PhD, ATC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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