Actively Recruiting

Age: 18Years - 85Years
All Genders
NCT04612322

MICRO: a Registry Study in Patients With Microvascular Angina

Led by Johannes Gutenberg University Mainz · Updated on 2022-03-31

1000

Participants Needed

1

Research Sites

469 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The evidence above demonstrates that microvascular dysfunction is an important determinant of patient prognosis, which however remains poorly classified. Given the high burden of disease and the severity of the functional impairment in these patients, the lack of a clear definition for this disease has a potentially large clinical importance. It is important to better describe the phenotype of these patients, identify the predictors of prognosis, and determine the impact of diagnosis.

CONDITIONS

Official Title

MICRO: a Registry Study in Patients With Microvascular Angina

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to less than 85 years
  • Chronic coronary syndrome including anginal equivalents
  • Angina classified as CCS class II to IV
  • Evidence of reversible ischemia on non-invasive testing
  • Availability of measurements including index of microvascular resistances, resting full-cycle ratio, fractional flow reserve, and coronary flow reserve
  • Ability and willingness to understand and sign informed consent prior to procedure
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Medical or psychological conditions that would prevent proper participation
  • Left ventricular ejection fraction less than 30%
  • Previous coronary artery bypass surgery to all major branches in the LAD and LCX territory preventing measurement of index of microvascular resistances
  • Decompensated congestive heart failure
  • Chronic or acute renal failure with creatinine greater than 2 mg/dl
  • Severe valvular heart disease
  • Comorbidities limiting life expectancy to less than one year

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitätsmedizin Mainz

Mainz, RLP, Germany, 55131

Actively Recruiting

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Research Team

T

Tommaso Gori, Dott med, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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