Actively Recruiting
Micro-transplantation in Elderly Patients With Acute Myeloid Leukemia
Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-04-09
21
Participants Needed
7
Research Sites
468 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire de Saint Etienne
Lead Sponsor
I
Institut de Cancérologie de la Loire
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims at evaluating the safety and the tolerance of the micro-transplantation in elderly patients with acute myeloid leukemia who are ineligible to conventional allogeneic transplantation.
CONDITIONS
Official Title
Micro-transplantation in Elderly Patients With Acute Myeloid Leukemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient affiliated to a social security regimen or beneficiary of the same
- Signed written informed consent form
- Patient aged 60 years or older and less than 75 years
- Established diagnosis of de novo or secondary AML with intermediate-risk or adverse-risk cytogenetic profile, or myelodysplasic syndromes (RAEB)
- Pathologically confirmed complete remission after anti-leukemic induction therapy with less than 5% blasts
- Contraindication to conditioning regimen in conventional allogeneic transplantation
You will not qualify if you...
- Established diagnosis of acute myeloid leukemia with standard-risk cytogenetic profile
- Promyelocytic leukemia t(15;17)
- CBF-AML t(8;21) or inv(16)
- Normal karyotype with a favorable molecular profile: NPM1+ and FLT3-; NPM1+, FLT3- and double mutation CEBPα or chronic myeloid leukemia in blastic phase
- Patient under guardianship or deprived of liberty or any condition affecting ability to understand and sign informed consent
- Refusing participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
CHU Estaing
Clermont-Ferrand, France, 63000
Actively Recruiting
2
Centre Hospitalier Universitaire de Grenoble
Grenoble, France
Actively Recruiting
3
CHRU de Lille
Lille, France
Not Yet Recruiting
4
Centre Hospitalier Lyon Sud
Lyon, France
Actively Recruiting
5
Centre Hospitalier Universitaire de Nancy
Nancy, France
Not Yet Recruiting
6
Hôpital de la Pitié-Salpêtrière
Paris, France
Not Yet Recruiting
7
CHU de Saint-Etienne
Saint-Etienne, France, 42055
Actively Recruiting
Research Team
J
Jérôme Cornillon, MD
CONTACT
E
Elisabeth Daguenet, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here