Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT05558241

Micro-UltraSound In Cancer - Active Surveillance

Led by University of Alberta · Updated on 2026-04-13

210

Participants Needed

5

Research Sites

556 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.

CONDITIONS

Official Title

Micro-UltraSound In Cancer - Active Surveillance

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult men with Gleason Grade Group 1 prostate cancer managed by active surveillance who require a confirmatory prostate biopsy
Not Eligible

You will not qualify if you...

  • Men who cannot undergo a prostate MRI
  • Men who cannot undergo a prostate biopsy

AI-Screening

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Trial Site Locations

Total: 5 locations

1

University of California Los Angeles, Department of Urology

Los Angeles, California, United States, 90095

Actively Recruiting

2

Kipnes Urology Centre - Kaye Edmonton Clinic

Edmonton, Alberta, Canada, T6G1Z1

Actively Recruiting

3

University of British Columbia

Vancouver, Alberta, Canada, V6T 1Z3

Actively Recruiting

4

CIUSSS du Nord-de-L'Ile-De-Montreal

Montreal, Quebec, Canada, H3L 1K5

Actively Recruiting

5

Humanitas

Milan, Italy

Actively Recruiting

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Research Team

A

Adam Kinnaird, MD, PhD

CONTACT

S

Stacey Broomfield, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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