Actively Recruiting
Microbiota in Gastric Cancer by Gastric Mucosal Brushing
Led by King Chulalongkorn Memorial Hospital · Updated on 2024-05-07
40
Participants Needed
2
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many studies have shown a significant change of diversity and composition in gut microbiota across the gastric carcinogenesis process, particularly in patients with gastric cancer. However, there has been no analysis of gastric microbiota using the mucosal brushing technique, despite its favoring benefit in microbiota study. Therefore, this study aims to evaluate microbiota profile in patients with gastric cancer, compared to those without gastric cancer by using mucosal brush sampling. This will improve current knowledge of the potential role of the microbiome in patient gastric cancer as a future biomarker marker using brushing sampling.
CONDITIONS
Official Title
Microbiota in Gastric Cancer by Gastric Mucosal Brushing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years of age or older) undergoing esophagogastroduodenoscopy (EGD)
- Gastric cancer group: patients with pathological diagnosis of high-grade dysplasia or gastric cancer
- Control group: patients with no or minimal upper gastrointestinal symptoms and normal or minimal gastritis appearance on current EGD
- Provided informed consent
You will not qualify if you...
- History of gastrointestinal or hepatobiliary surgery
- Use of antibiotics or probiotics within the last 4 weeks
- Use of proton pump inhibitors (PPI) within the last 2 weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
King Chulalongkorn Memorial Hospital
Bangkok, Thailand, 10330
Actively Recruiting
2
King Chulalongkorn memorial hospital
Bangkok, Thailand, 10330
Actively Recruiting
Research Team
T
Thanrada Vimonsuntirungsri, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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