Actively Recruiting
Microfluidic Chip Method Versus Density Gradient Centrifugation Method on Semen Parameters
Led by Professor Ernest Hung-Yu Ng · Updated on 2024-12-05
80
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Infertility affects many couples, with male infertility being a common cause. In vitro fertilization (IVF) is an effective treatment, but its success rates are not high. Semen quality can affect IVF outcomes, and the current method used to process semen can damage the sperm and DNA. Scientists are now testing a new method called microfluidic chip technology, which reduces DNA damage and increases sperm movement. This study will compare the effectiveness of the chip method and the current method on semen quality in men attending a fertility clinic. The study will randomly assign semen collected to one of the two methods and assess the semen quality using different tests, as well as the difference in using two different microfluidic chip platform . The primary outcome will be DNA fragmentation, and other outcomes include sperm count and motility. Semen samples would be collected from study subjects for analysis and that both the samples and results would not be used in patients' treatment.
CONDITIONS
Official Title
Microfluidic Chip Method Versus Density Gradient Centrifugation Method on Semen Parameters
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Sperm concentration of the raw semen with at least 5 million motile sperm per ml with a total volume of not less than 1.5ml.
You will not qualify if you...
- Sperm concentration of the raw semen of less than 5 million motile sperm per ml
- Men unable to provide an ejaculated semen sample
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Obstetrics and Gynaecology
Hong Kong, Hong Kong, China
Actively Recruiting
Research Team
Y
YU WING TONG, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here