Actively Recruiting
Microfluidic Chip Method Versus Density-gradient Centrifugation Method in IVF
Led by Professor Ernest Hung-Yu Ng · Updated on 2024-12-06
1136
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Infertile patients attending IVF treatment at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF. Subsequently, they will be randomly assigned on the day of oocyte retrieval by a laboratory staff into one of the following two groups: (1) the microfluidic chip group and (2) the density gradient group for sperm preparation and subsequent use in fertilization. Other IVF procedures will be the same as our usual practice. Both patients and clinicians were blinded from the group allocation i.e. a double blind study. The primary outcome is the cumulative live birth rate defined as the number of pregnancies leading to live birth within 6 months of randomisation.
CONDITIONS
Official Title
Microfluidic Chip Method Versus Density-gradient Centrifugation Method in IVF
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infertile women aged under 43 years at the time of ovarian stimulation for IVF
You will not qualify if you...
- Women undergoing preimplantation genetic testing for monogenic diseases, structural chromosome rearrangements, or aneuploidy
- Male factor infertility requiring surgical sperm retrieval such as microscopic epididymal sperm aspiration or testicular sperm extraction
- Use of donor oocytes or donor sperm
- Presence of submucosal fibroid or hydrosalpinx on pelvic scan that has not been surgically treated
- Women previously recruited into this study
- Women participating in other randomized trials
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Obstetrics and Gynaecology
Hong Kong, Hong Kong, China
Actively Recruiting
Research Team
Y
YU WING TONG, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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