Actively Recruiting
Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders
Led by Northwestern University · Updated on 2026-05-12
18
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will examine whether a combination of breathing training during wake and targeted reactivation of the training during sleep can induce breathing changes during sleep and subsequent cognitive benefits during wake. Participants with obstructive sleep apnea (who have not yet been treated for sleep apnea) will be recruited. Participants will engage in breath training for one week in their own homes and to record their sleep at home using commercially available mobile devices and subsequently have their sleep monitored for one night of polysomnography recordings plus targeted reactivation in a laboratory setting.
CONDITIONS
Official Title
Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Right-handed, English-speaking adults aged 18 to 60 years with normal hearing during sleep
- Participants with suspected obstructive sleep apnea (OSA), including physician-diagnosed cases or those with intermediate to high risk based on STOP-BANG questionnaire
- No other reported sleep disorders besides OSA
- No neurological or cardiometabolic diseases or disorders
- Not currently undergoing active treatment for sleep apnea
- Body mass index (BMI) less than or equal to 40
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
K
Ken A Paller, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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