Actively Recruiting
Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation
Led by Cairo University · Updated on 2026-01-22
32
Participants Needed
3
Research Sites
57 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups. Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively. Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation. Control Group (Group B): microneedling will be done alone for depigmentation.
CONDITIONS
Official Title
Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients exhibiting melanin hyperpigmentation in the anterior region of the upper or lower gingiva.
- Age 18 years or older.
- Patients should be free from any systemic diseases according to modified Cornell Medical index.
- Non-smokers
You will not qualify if you...
- Fully edentulous patients.
- Patients with endocrine disorders causing hyperpigmentation or drug induced gingival pigmentation.
- Pregnant or lactating females.
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Cairo university
Cairo, El Manial, Egypt, 11562
Actively Recruiting
2
Faculity of Dentistry, Cairo university
Cairo, El Manyl, Egypt, 11555
Actively Recruiting
3
Faculity of Dentistry, Cairo university
Cairo, El Manyl, Egypt, 11555
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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