Actively Recruiting
Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
Led by Alexandria University · Updated on 2024-07-30
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of microneedling combined with regular insulin application compared to microneedling alone on atrophic scars. The study addresses limitations of previous research by including a control group receiving microneedling with saline instead of insulin. This randomized trial aims to better understand whether adding insulin enhances the regenerative effects on scars caused by trauma or surgery. The study involves two groups: one receiving microneedling with topical insulin applied to the scar, and another receiving microneedling with a saline solution. Treatments are performed directly on the scar tissue. This design allows comparison of the effects of microneedling augmented by protein-rich insulin versus microneedling alone. Participants aged 12 to 60 years with completely healed atrophic scars will be monitored for changes in their scars over a 4-month period. Researchers will assess scar improvement to measure the primary outcome. Safety and other effects will be observed throughout the study until its completion in December 2024.
CONDITIONS
Brief Title
Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 12 to 60 years
- Atrophic scars caused by trauma or surgery
- Scars must be completely healed
You will not qualify if you...
- History or tendency for hypertrophic or keloidal scars
- Treatment received for the scar in the past 3 months
- Diabetes or history of abnormal blood sugar levels
- Pregnant or breastfeeding females
- Active infection at the scar site
- Current or recent (within 1 month) isotretinoin treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 4 months
Participants receive microneedling on their atrophic scars with either topical regular insulin or saline applied during the procedure.
Trial Site Locations
Total: 1 location
1
Alexandria University, Faculty of Medicine
Alexandria, Egypt
Actively Recruiting
Research Team
D
Dalia I Halwag, PhD, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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