Actively Recruiting

Age: 18Years +
All Genders
NCT07295704

Micropulse Laser in Treatment of Initial and Refractory Cases of Center-Involved Diabetic Macular Edema

Led by The General Authority for Teaching Hospitals and Institutes · Updated on 2025-12-22

50

Participants Needed

1

Research Sites

23 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effect of subthreshold 577 nm micropulse laser photocoagulation in the treatment of initial and refractory cases of Center-Involved Diabetic Macular Edema.

CONDITIONS

Official Title

Micropulse Laser in Treatment of Initial and Refractory Cases of Center-Involved Diabetic Macular Edema

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Both males and females
  • Diagnosis of type 1 or type 2 diabetes mellitus
  • Best-corrected visual acuity of 20/400 or better
  • Center-involved diabetic macular edema with central macular thickness between >250 and <700 micrometers measured by spectral-domain optical coherence tomography
  • Any level of non-proliferative diabetic retinopathy or proliferative diabetic retinopathy with adequate panretinal photocoagulation and no signs of active disease based on fluorescein angiography
Not Eligible

You will not qualify if you...

  • Having only one functioning eye (monocular)
  • Chronic renal failure or history of renal transplant due to diabetic nephropathy
  • Glycated hemoglobin (HbA1c) level greater than 10%
  • Presence of vitreomacular traction syndrome
  • Presence of epiretinal membrane
  • Panretinal photocoagulation within 4 months prior to treatment
  • Intraocular surgery within 6 months prior to treatment, including cataract or vitreoretinal surgery
  • Presence of rubeosis iridis
  • Severe glaucoma
  • High-risk proliferative diabetic retinopathy
  • Poor pupil dilation
  • Increased foveal avascular zone
  • Any condition that could interfere with optical coherence tomography measurements or visual acuity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

the General Authority for Teaching Hospitals and Institutes

Cairo, Egypt, 11562

Actively Recruiting

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Research Team

H

Hossam A Hassan, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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