Actively Recruiting

Phase 4
Age: 21Years +
All Genders
NCT04589442

Microsurfaced Grafts in Deep Burn Wounds

Led by CellTherX · Updated on 2021-01-15

20

Participants Needed

1

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is designed as a prospective, randomized, within subject controlled design to evaluate the effectiveness of Microsurfaced vs Control cadaveric grafts for coverage of acute deep-partial or full-thickness burn wounds to promote wound healing. This study will be performed in 2 parts: Time to wound bed preparedness through 6 weeks (Part A) and wound site healing, graft take and long-term scar outcomes (Part B). Subjects will be treated with both control and microsurfaced cadaveric grafts on adjacent deep-partial or full-thickness burn wounds.

CONDITIONS

Official Title

Microsurfaced Grafts in Deep Burn Wounds

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent by patient or legally authorized representative
  • Deep partial or full thickness burn injury from flame, scald, or contact burn
  • Burn site large enough to place both control and microsurfaced grafts (minimum 4 cm2 each) on the same or two separate sites
  • Total body surface area burned is 30% or less
  • Admission to treatment within 72 hours of burn injury
  • Non-infected wound at admission as diagnosed by physician
  • Treated as outpatient or in observational setting
  • Age 21 years or older
Not Eligible

You will not qualify if you...

  • Burns involving the face
  • Burns caused by electrical, chemical, or frostbite injuries
  • Admission to treatment more than 72 hours after injury
  • Wounds infected at admission
  • Pregnant or planning to become pregnant
  • Nursing or actively lactating
  • Developmental disability or significant psychological disorder impairing consent or participation, including untreated schizophrenia, bipolar disorder, or recent psychiatric hospitalization
  • Active alcohol or substance abuse impairing study participation
  • Any medical condition or co-morbidity preventing successful study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Joseph M Still Research Foundation

Augusta, Georgia, United States, 30909

Actively Recruiting

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Research Team

J

Joan Wilson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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