Actively Recruiting
Microwave Ablation Versus Liver Resection for Intrahepatic Cholangiocarcinoma
Led by Chinese PLA General Hospital · Updated on 2024-07-25
1000
Participants Needed
1
Research Sites
1065 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Thermal ablation has been recommended by worldwide guidelines as first-line treatment for hepatocellular carcinoma (HCC), while evidence regarding its efficacy for primary intrahepatic cholangiocarcinoma (iCCA) is lacking. The goal of this observational study is to study the efficacy of ablation in treating iCCA by comparing its prognosis with surgery. The main questions it aims to answer are: * Whether microwave ablation could achieve similar efficacy with liver resection in treating iCCA * What is the risk factor for ablation or surgery in treating iCCA * What kind of iCCA patients could receive ablation as their first-line treatment In this real-world multicenter cohort study, we will collect data of iCCA patients from hospitals who underwent microwave ablation (MWA) or liver resection (LR) for tumors within Milan criteria. Survival will be compared between patients treated by MWA or LR.
CONDITIONS
Official Title
Microwave Ablation Versus Liver Resection for Intrahepatic Cholangiocarcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pathologically diagnosed intrahepatic cholangiocarcinoma (iCCA) based on WHO classifications
- Curative-intent treatment with liver resection or microwave ablation
- Tumor within Milan criteria: single tumor 5 cm or less; up to 3 tumors each 3 cm or less; no major vascular or hilar invasion; no extrahepatic or lymphatic metastasis or other malignancies
- Age 18 years or older
You will not qualify if you...
- Not meeting any one of the inclusion criteria
AI-Screening
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Trial Site Locations
Total: 1 location
1
Chinese PLA General Hospital
Beijing, Beijing Municipality, China, 100853
Actively Recruiting
Research Team
C
Chuan Pang, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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