Actively Recruiting

Phase Not Applicable
Age: 5Years - 18Years
All Genders
NCT07000656

Micturition Desire-Relaxation Training Device for Lower Urinary Tract Dysfunction in Children

Led by Shanghai Children's Medical Center · Updated on 2025-06-05

200

Participants Needed

1

Research Sites

79 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Urine storage and voiding are fundamental physiological processes. In clinical settings, many cases of lower urinary tract dysfunction (LUTD) are closely associated with abnormal conditioned reflexes formed in the central nervous system during the urine storage or voiding phases. Relaxation, as a core physiological and psychological state, has been shown to promote effective urine storage and facilitate smooth voiding. By repeatedly training individuals to establish a new conditioned reflex linking the sensation of urinary urgency with a state of relaxation, it may be possible to improve bladder storage capacity and voiding function. Based on this concept, the investigators have developed the world's first Micturition Desire-Relaxation Training Device (Chinese Patent No.: ZL 2020 1 0397789.4). This study aims to evaluate the clinical efficacy of this device in treating LUTD in children.

CONDITIONS

Official Title

Micturition Desire-Relaxation Training Device for Lower Urinary Tract Dysfunction in Children

Who Can Participate

Age: 5Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of nocturnal enuresis with at least one episode of involuntary nighttime urination per month for over 3 months
  • No abnormalities in routine urinalysis and no bedwetting-free periods longer than 6 months unless due to organic disease
  • Diagnosis of daytime urinary incontinence with at least one episode of intermittent urinary leakage during wakefulness per month for over 3 months
  • No anatomical or neurological causes of urinary incontinence
  • Diagnosis of urinary frequency involving frequent small volume urination during day and before sleep, with normal total daily urine volume
  • Age between 5 and 18 years, any gender
  • Voluntary participation with informed consent signed by child and guardian
Not Eligible

You will not qualify if you...

  • Enuresis caused by urinary tract infections, pinworms, myelitis, spinal cord injuries, epilepsy, cerebral developmental disorders, diabetes, or other neurological, urinary, or endocrine diseases
  • Transient enuresis due to excessive activity, mental fatigue, or excessive fluid intake before bedtime
  • Urinary frequency caused by neurogenic bladder, urinary tract infections, urethral syndrome, hypercalciuria, or metabolic diseases
  • Participation in other clinical trials within the past month
  • Any condition deemed unsuitable for trial participation by the investigator

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Micturition Desire-Relaxation Training

Shanghai, Shanghai Municipality, China, 200122

Actively Recruiting

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Research Team

J

jun ma

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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