Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT06320899

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

Led by SpineSave AG · Updated on 2024-06-25

126

Participants Needed

2

Research Sites

377 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results. The primary aim is to compare the reduction in back pain after the treatment with high- or mid-flex rods with that after treatment with low-flex rods. Secondary, the functionality after treatment with high- or mid-flex rods will be compared to that after treatment with low-flex rods.

CONDITIONS

Official Title

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Degenerative symptoms in 1 to 2 lumbar spine segments from L1 to S1
  • Signed informed consent from participant
  • Participant agrees to attend follow-up visits
  • Body-Mass-Index less than 32
  • Pedicle screw axis distance less than 30 mm
  • Presence of at least one of the following: dynamic spinal canal stenosis, neuroforaminal stenosis, facet joint syndrome or spondylarthrosis, discopathy including recurrent disc hernia, degenerative spondylolisthesis (Meyerding grade less than 1), or lumbar spine instability (hypermobility or hypomobility if decompressed)
Not Eligible

You will not qualify if you...

  • Missing bone structure due to congenital anomalies or severe anatomical deformities preventing implant anchoring
  • Damaged structural tissue such as from a bone fracture
  • Condition affecting the thoracic or cervical spine
  • Pronounced idiopathic scoliosis
  • Spondylolisthesis with Meyerding grade greater than 1
  • Isthmic spondylolysis
  • Bone tumor
  • Osteochondrosis Modic type I, II, or III
  • Osteoporosis impairing screw anchoring
  • History of third-party implants
  • Active local or systemic infection
  • Known allergy to titanium alloys
  • Growing skeleton with open epiphyseal joints
  • Severe muscular, neuronal, or vascular disease
  • Immunosuppressive therapy
  • Long-term cortisone therapy
  • Heavy smoking (more than six cigarettes daily), drug addiction, or alcoholism
  • Chronic pain conditions
  • Incapable of judgment or emergency situations
  • Implantation during pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Spital Aarberg

Aarberg, Switzerland, 3270

Actively Recruiting

2

Hirslanden Klinik Linde

Biel, Switzerland, 2501

Actively Recruiting

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Research Team

S

Sarah Abramovic

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases | DecenTrialz