Actively Recruiting
Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)
Led by University Hospital, Geneva · Updated on 2026-03-17
180
Participants Needed
2
Research Sites
97 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic Subdural Hematomas (cSHD) are common, and due to cerebral compression, often result in neurological impairment and reduced consciousness. Surgery is typically performed once neurological symptoms develop. Recent studies suggest that arteries nourished by the middle meningeal artery (MMA) may be responsible for hematoma progression and that MMA embolization is clinically useful. There is less evidence, that embolization of MMA also may be a treatment option for individuals without surgical treatment. The investigators propose a multicentre study to investigate both potentials: (1) Assessment of efficacy of embolization after surgery to reduce recurrence and improve outcomes by conducting a randomized trial (randomization arms; Arms 1 and 2), (2) Assessment of embolization-alone efficacy when surgery is contraindicated or refused (embolization-only arm, Arms 3 and 4).
CONDITIONS
Official Title
Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 100 years
- Ability to provide consent
- Chronic subdural hematoma located at the brain convexities
- Patients with symptomatic chronic subdural hematoma
- Patients with large chronic or subacute hematoma after 6 weeks of unsuccessful conservative treatment
You will not qualify if you...
- Unable to provide consent
- Pregnancy
- Prisoner
- Contraindication to angiography
- Difficulty with follow-up (e.g., distant residency, homelessness)
- Previous surgery for chronic subdural hematoma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Geneva University Hospitals
Geneva, Switzerland
Actively Recruiting
2
EOC
Lugano, Switzerland
Actively Recruiting
Research Team
A
Aria Nouri
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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