Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT06008561

Midwest Birth Outcomes and Indigenous American Pregnancy

Led by Sanford Health · Updated on 2026-03-20

80

Participants Needed

2

Research Sites

163 weeks

Total Duration

On this page

Sponsors

S

Sanford Health

Lead Sponsor

N

National Institute of General Medical Sciences (NIGMS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Indigenous American pregnancies in the Midwest have disproportionally high rates of adverse outcomes, however little research has been done on how historical trauma and stress may impact these adverse outcomes. This project gathers data from pregnant Indigenous American women on their experiences with historical trauma, stress, and birth outcomes, as well as physiological data of how they respond to stress, in order to better understand the associations between these factors and the biological mechanisms underlying them. Understanding the mechanisms by which both historical and proximal stress "get under the skin" and influence pregnancy health and perinatal outcomes, will afford new targets of intervention to help reduce these IA health disparities.

CONDITIONS

Official Title

Midwest Birth Outcomes and Indigenous American Pregnancy

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years old
  • Less than 26 weeks pregnant
  • Healthy single baby pregnancy
  • Indigenous American
Not Eligible

You will not qualify if you...

  • Use of assistive reproductive technology (in-vitro fertilization)
  • History of cardiac disease
  • History of endocrine disease

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Sanford Health

Fargo, North Dakota, United States, 58104

Actively Recruiting

2

Sanford Health

Sioux Falls, South Dakota, United States, 57104

Actively Recruiting

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Research Team

G

Grace Biermann, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Midwest Birth Outcomes and Indigenous American Pregnancy | DecenTrialz