Actively Recruiting

Phase 1
Age: 18Years - 45Years
FEMALE
Healthy Volunteers
NCT06502158

Mifepristone vs Misoprostol

Led by Montefiore Medical Center · Updated on 2025-08-13

94

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of patients who achieve successful cervical dilation will be different between the study groups.

CONDITIONS

Official Title

Mifepristone vs Misoprostol

Who Can Participate

Age: 18Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • English or Spanish-speaking
  • Ability to give informed consent
  • Seeking an induced abortion of a singleton pregnancy
  • Pregnancy between 12 weeks, 0 days and 16 weeks, 6 days at time of surgery
Not Eligible

You will not qualify if you...

  • History of more than two prior Cesarean deliveries
  • Sonographic evidence of placenta previa
  • Sonographic concern for morbidly adherent placenta
  • Prior obstetric hemorrhage requiring transfusion
  • Obstructive cervical or lower uterine segment fibroid
  • Current use of therapeutic anticoagulation
  • Cerclage in place
  • History of more than one prior cervical excisional procedure
  • Body mass index greater than 50 kg/m^2

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Montefiore Medical Center

The Bronx, New York, United States, 10467

Actively Recruiting

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Research Team

L

Laura Fletcher, MD, MPH

CONTACT

A

Antoinette Danvers, MD, MSCR, MBA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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