Actively Recruiting
Migraine in Adolescents
Led by Washington University School of Medicine · Updated on 2025-08-13
250
Participants Needed
1
Research Sites
354 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Aim 1. To identify psychophysical and neural factors predicting migraine onset in adolescents Aim 2a. To determine hormonal, psychophysical, and neural changes associated with migraine onset. Aim 2b. To identify the temporal relationships between hormonal, psychophysical, and neural changes preceding vs. following migraine onset. Aim 3. To identify psychophysical and neural factors predicting migraine prognosis in adolescents with migraine.
CONDITIONS
Official Title
Migraine in Adolescents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 10 to 13 years
- Biological male or female
- For healthy participants: no migraine diagnosis or symptoms
- For healthy participants: either have or do not have a first-degree relative with migraine
- For migraine participants: diagnosed with migraine or have migraine symptoms
- For migraine participants: migraine duration longer than 6 months
- For migraine participants: no preventative treatment or stable preventative treatment for at least 6 months
You will not qualify if you...
- Diagnosis of any chronic pain syndrome (other than migraine for migraine group)
- Diagnosis of neurological, developmental, pubertal, or psychiatric disorder
- Regular use of pain or psychiatric medications (healthy group only)
- MRI contraindications such as metal in the body or claustrophobia
- Inability to understand and communicate in English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
A
Alana McMichael, MA
CONTACT
H
Hadas Nahman-Averbuch
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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