Actively Recruiting
MIND Foods and Aerobic Training in Black Adults With HTN
Led by Indiana University · Updated on 2026-02-05
128
Participants Needed
1
Research Sites
235 weeks
Total Duration
On this page
Sponsors
I
Indiana University
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition. Participants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires. Participants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.
CONDITIONS
Official Title
MIND Foods and Aerobic Training in Black Adults With HTN
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fluent in English
- Resident of Marion County
- Aged 35 to 75 years
- Self-identified as non-Hispanic Black, African-American, biracial including African-American
- Systolic blood pressure of 140 mm Hg or higher in past 12 months
- Ability to see and read street signs (self-reported)
- Stable housing with independent access to kitchen including functional stove or hotplate, oven, refrigerator, and freezer (self-reported)
- Independent in daily activities with less than 3 responses of "Require Assistance" and no responses of "Dependent" on the functional activities questionnaire
- Normal cognition with six-item screener score of 5 or higher
- Less than 20 minutes of moderate or vigorous physical activity on a usual day
- Able to exercise safely as per abbreviated Exercise Assessment for You or clearance from primary care provider
- Average systolic blood pressure of 130 mm Hg or higher from 3 standardized measurements by research staff
You will not qualify if you...
- Living in a nursing home
- Diagnosis of dementia, Alzheimer disease, mild cognitive impairment, Parkinson disease, brain tumor, brain infection, or brain surgery within last 10 years with residual symptoms
- Cancer with short life expectancy or currently undergoing chemotherapy or radiation therapy
- Psychosis, schizophrenia, or bipolar disorder
- Diagnosed hypertensive heart disease, hypertensive chronic kidney disease, or related ICD 10 codes I11, I12, I13, I15, or I16
- Current or past use of donepezil, memantine, rivastigmine, or galantamine
- Alcohol consumption of 8 or more drinks per week for women or 15 or more for men
- Drug use or abuse excluding marijuana
- Planning to move out of the area during the study
- Scheduling conflicts with intervention
- Unwillingness to use a touchscreen or video conferencing
- Low communicative ability or functional status interfering with interventions
- Unable to provide informed consent
- Participation in any lifestyle modification or weight loss program such as Weight Watchers
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Eskenazi Health
Indianapolis, Indiana, United States, 46202
Actively Recruiting
Research Team
D
Daniel O Clark, PhD
CONTACT
L
Lyndsi R Moser, BA, CCRP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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